STAT3 (phospho Y705) polyclonal antibody
产品名称： STAT3 (phospho Y705) polyclonal antibody
英文名称： STAT3 (phospho Y705) polyclonal antibody
产品编号： PAB24732
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152
- 传真 : +886-2-8751-1186
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic phosphopeptide of STAT3.
- Immunogen:
- Synthetic phosphopeptide corresponding to residues surrounding Y705 of STAT3.
- Host:
- Rabbit
- Theoretical MW (kDa):
- ~88.0
- Reactivity:
- Human, Mouse
- Specificity:
- STAT3 (phospho Y705) polyclonal antibody detects endogenous levels of STAT3 protein.
- Form:
- Liquid
- Purification:
- Antigen affinity purification
- Concentration:
- 1 mg/mL
- Storage Buffer:
- In PBS, pH 7.2 (15 mM sodium azide)
- Storage Instruction:
- Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- Western Blot (1:500-1:1000)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Entrez GeneID:
- 6774
- Gene Name:
- STAT3
- Gene Alias:
- APRF,FLJ20882,HIES,MGC16063
- Gene Description:
- signal transducer and activator of transcription 3 (acute-phase response factor)
- Omim ID:
- 102582
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated through phosphorylation in response to various cytokines and growth factors including IFNs, EGF, IL5, IL6, HGF, LIF and BMP2. This protein mediates the expression of a variety of genes in response to cell stimuli, and thus plays a key role in many cellular processes such as cell growth and apoptosis. The small GTPase Rac1 has been shown to bind and regulate the activity of this protein. PIAS3 protein is a specific inhibitor of this protein. Three alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq
- Other Designations:
- DNA-binding protein APRF,acute-phase response factor,signal transducer and activator of transcription 3
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