(R,S)-Ivosidenib ((R,S)-AG-120)
国际站:(R,S)-Ivosidenib ((R,S)-AG-120)
CAS:2070009-31-1
纯度:98.49%
分子量:582.96
Formula:C28H22ClF3N6O3
运输条件:Room temperature in continental US; may vary elsewhere.
储存方式:
Powder | -20°C | 3 years |
---|---|---|
4°C | 2 years | |
In solvent | -80°C | 2 years |
-20°C | 1 year |
产品活性:(R,S)-Ivosidenib ((R,S)-AG-120) 是 Ivosidenib (AG-120) 的对映体,活性较低。
生物活性:(R,S)-Ivosidenib ((R,S)-AG-120)是Ivosidenib (AG-120)活性较低的对映体[1]。
参考文献:[1]. Popovici-Muller J, et al. Discovery of AG-120 (Ivosidenib): A First-in-Class Mutant IDH1 Inhibitor for the Treatment of IDH1Mutant Cancers. ACS Med Chem Lett. 2018 Jan 19;9(4):300-305.