AP1867
MCE 国际站:AP1867
CAS:195514-23-9
品牌:MedChemExpress (MCE)
存储条件:Powder: -20°C, 3 years; 4°C, 2 years.In solvent: -80°C, 6 months; -20°C, 1 month.
生物活性:AP1867 是一种合成的 FKBP12F36V 定向配体[1]。 IC50 和目标:FKBP[1] 体外 AP1867 与野生型 FKBP (Kd = 67 纳米)[2]。
体外:AP1867 与野生型 FKBP (Kd = 67 nM)[2] 结合。
热销产品:Enoxaparin | Resorufin sodium salt | 14-3-3 beta, Human | 8-CPT-Cyclic AMP (sodium) | KT203 | Tricin | Enzastaurin | BODIPY-FL | PNGase F | Proadifen (hydrochloride)
研究领域:Apoptosis | Immunology/Inflammation | Autophagy
作用靶点:FKBP
热门产品线:重组蛋白 | 化合物库 | 天然产物 | 荧光染料 | PROTAC | 同位素标记物 | 寡核苷酸
Trending products:Recombinant Proteins | Bioactive Screening Libraries | Natural Products | Fluorescent Dye | PROTAC | Isotope-Labeled Compounds | Oligonucleotides
参考文献:
[1]. Nabet B, et al. The dTAG system for immediate and target-specific protein degradation. Nat Chem Biol. 2018 May;14(5):431-441.[2]. Koide K, et al. A synthetic library of cell-permeable molecules. J Am Chem Soc. 2001 Jan 24;123(3):398-408.